Preheat Oven or Skillet:
If baking, preheat oven to 400°F (200°C). If pan-searing, heat oil in a nonstick skillet over medium-high heat.
Make the Sauce:
In a small bowl, whisk together hot sauce, brown sugar, soy sauce, garlic, vinegar, and red pepper flakes until smooth.
Season Salmon:
Pat salmon dry and season with salt and pepper.
Cook the Salmon:
To Bake: Place salmon in a parchment-lined or greased baking dish. Brush generously with the firecracker sauce. Bake for 10–12 minutes or until salmon flakes easily.
To Pan-Sear: Sear salmon skin-side up for 3–4 minutes, flip, then pour sauce into the pan and cook another 3–4 minutes, basting as it reduces and thickens.
Serve:
Spoon remaining sauce over salmon and serve hot with rice, quinoa, or steamed vegetables.